Nuevas tendencias de andamios en los procedimientos regenerativos endodónticos. Revisión bibliográfica
DOI:
https://doi.org/10.54139/odous.v22i1.83Palabras clave:
regeneración endodóntica, células madre, PRP, concentrados plaquetarios, L-PRF, A- PRFResumen
La regeneración endodóntica (RE) se basa en el concepto de ingeniería tisular para restaurar el sistema de conductos a un estado saludable, buscando el desarrollo radicular continuo y del tejido circundante, e involucra componentes que incluyen células madre, factores de crecimiento y andamiajes, siendo estos últimos un elemento importante, sumamente estudiado. Definido como el soporte, vehículo de entrega o la combinación de materiales y biomoléculas con tecnología avanzada que facilitan la migración, unión y transporte celular. Exhibiendo beneficios como la estimulación para la producción de colágeno, diferenciación, proliferación y migración celular, angiogénesis, propiedades antibacterianas y antiinflamatorias. La presente investigación documental de diseño bibliográfico tuvo como objetivo analizar las nuevas tendencias de andamios dentro de los procedimientos regenerativos endodónticos (PRE), a través de la descripción del papel que juegan los diferentes componentes de la triada, enumerando, y explicando los beneficios de los diferentes andamios, y definiendo el de mayor ventaja. Basado en la revisión de artículos de revistas científicas indexadas, a través de la búsqueda electrónica en PubMed, ScienceDirect, Medline, Scielo y Google Académico; se consideró que la vascularización inadecuada, infección, procedimientos engorrosos, degradabilidad incierta, baja estabilidad, rigidez y resistencia representan un desafío importante. Conclusión: los concentrados plaquetarios de segunda generación, más recientes y optimizados (L-PRF y A-PRF) son las matrices que liberan mayor cantidad de plaquetas y factores de crecimiento, son de fácil preparación, presentan un mejor comportamiento del linaje fagocítico, disminuyen edema y dolor postoperatorio, aportando mejores resultados dentro de los PRE.
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